Nicholas Renzette, Ph.D.
Instructor
University of Massachusetts Medical School
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17. Jiang, L., Liu, P., Bank, C., Renzette, N., Prachanronarong, K., Yilmaz, L.S., Caffrey, D.R., Zeldovich, K.B., Schiffer, C.A., Kowalik, T.F., Jensen, J.D., Finberg, R.W., Wang, J.P., Bolon, D.N.A. (2014) A balance between inhibitor binding and substrate processing confers influenza drug resistance. Journal of Molecular Biology. In Press.
16. Renzette, N., Kowalik, T.F., Jensen, J.D. (2015) On the relative roles of background selection and genetic hitchhiking in shaping human cytomegalovirus genetic diversity. Molecular Ecology. DOI: 10.1111/mec.13331. PMCID: In Process.
15. Renzette, N., Pokalyuk, C., Gibson, L., Bhattacharjee, B., Schleiss, M.R., Hamprecht, Yamamoto, A.Y., K., Mussi-Pinhata, M.M., Britt, W.R., Jensen, J.D., Kowalik, T.F. (2015) The Limits and Patterns of Human Cytomegalovirus Genetic Diversity in Humans. Proceedings of the National Academy of Sciences. 112: E4120-4128. PMCID: PMC4522815.
*Selected for “In This Issue” Highlight
14. Zeldovich, K.B., Liu, P., Renzette, N., Pham, S.T., Venev, S.V., Bolon, D.N., Kurt-Jones, E.A., Gallagher, G.R., Jensen, J.D., Caffrey, D.R., Schiffer, C.A., Kowalik, T.F., Wang, J.P., Finberg, R.W. (2014) Positive Selection Drives Preferred Segment Combinations During Influenza Virus Reassortment. Molecular Biology and Evolution.32(6):1519-1532.
*Featured on the Cover: http://mbe.oxfordjournals.org/content/32/6/local/front-matter.pdf
13. Renzette, N., Gibson, L., Jensen, J.D., Kowalik, T.F. (2014) Human Cytomegalovirus Intrahost Evolution – A New Avenue for Understanding and Controlling Herpesvirus Infections. Current Opinions in Virology. 10.1016/j.coviro.2014.08.001. PMCID: PMC4195796.
12. Foll, M., Poh, Y., Renzette, N., Ferrer-Admetlla, A., Shim, H., Malaspinas, A., Ewing, G., Bank, C., Liu, P., Wegmann, D., Caffrey, D.R., Zeldovich, K.B., Bolon, D.N., Wang, J.P., Kowalik, T.F., Schiffer, C.A., Finberg, R.W., Jensen, J.D. (2014) Influenza Drug Resistance: a Time-Sampled Population Genetics Perspective. PLoS Genetics. 10(2): e1004185, PMCID: PMC3937227.
11. Renzette, N., Somasundaran, M., Brewster, F., Coderre, J., Weiss, E.R., Greenough, T., Tabak, B., Garber, M., Kowalik, T.F., Luzuriaga, K. (2014) Intrahost EBV LMP1 genetic variability in peripheral blood B cells and oropharyngeal fluids. Journal of Virology. Epub Ahead of Print. doi: 10.1128/JVI.03378-13. PMCID: PMC3993555.
10. Renzette, N., Caffrey, D.R, Zeldovich, K.B., Liu, P., Gallagher, G.R., Aiello, D., Porter, A.J., Kurt-Jones, E.A., Bolon, D.N., Poh, Y., Jensen, J.D., Schiffer, C.A., Kowalik, T.F., Finberg, R.W., Wang, J.P. (2013) Evolution of the influenza A virus genome during development of oseltamivir resistance in vitro. Journal of Virology. doi:10.1128/JVI.01067-13, PMCID: PMC3911755.
9. Renzette, N., Gibson, L., Bhattacharjee, B., Fisher, D., Schleiss, M.R., Jensen, J.D., Kowalik, T.F. (2013) Rapid Intrahost Evolution of Human Cytomegalovirus is Shaped by Demography and Positive Selection. PLoS Genetics, 9(9): e1003735, PMCID: PMC3784496.
8. Bhattacharjee B, Renzette, N., Kowalik TF (2012) Genetic Analysis of Cytomegalovirus in Malignant Gliomas. Journal of Virology, 86: 6815-6824, PMCID: PMC3393585.
7. Renzette, N., Bhattacharjee, B., Jensen, J.D., Gibson, L., Kowalik, T.F. (2011) Extensive Genome-Wide Variability of Human Cytomegalovirus in Congenitally Infected Infants. PLoS Pathogens, 7(5): e1001344, PMCID: PMC3098220.
6. Long, E.W., Renzette, N., and Sandler, S.J. (2009) Suppression of Constitutive SOS Expression by recA4162 (I298V) and recA4164 (L126V) requires UvrD and RecX in Escherichia coli K-12. Molecular Microbiology 73: 226-39, PMCID: PMC2758083.
5. Long, E.W., Renzette, N., Centore, R.C and Sandler, S.J. (2008) Differential Requirements for Two recA Mutants for Constitutive SOS Expression in Esherichia coli K-12. PLoS One. 3(12): e4100, PMCID: PMC2605550.
4. Renzette, N., and Sandler, S.J. (2008) Requirements for ATP Binding and Hydrolysis in RecA Function in Escherichia coli. Molecular Microbiology 67: 1347-59.
3. Gruenig*, Renzette, N.*, M., Cox, M.M., and Sandler, S.J. (2008) RecA-mediated SOS induction requires an extended filament conformation but no ATP hydrolysis. Molecular Microbiology 69: 1165-79. PMCID: PMC2538424.
*Authors contributed equally to the work
2. Renzette, N., Gumlaw, N., and Sandler, S.J. (2006) DinI and RecX modulate RecA-DNA structures in Escherichia coli K-12. Molecular Microbiology 63: 103-115.
1. Renzette, N., Gumlaw, N., Nordman, J.T., Krieger, M., Yeh, S.P., Long, E., Centore, R., Boonsombat, R., and Sandler, S.J. (2005) Localization of RecA in Escherichia coli K-12 using RecA-GFP. Molecular Microbiology 57: 1074-1085.
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